PHA (poly-hydroxy-acids peelings)

PHA peel: photoagening, wrinkles, hyperpigmentation, dryness.

The lactobionic acid and gluconolactone belongs to next generation chemical peels


The PHA peels can help in photoagening, wrinkles, hyperpigmentation and dryness.

Polyhydroxylated acids have a greater molecular weight and structure; penetrate the skin gently and gradually. They provide additional moisture deeper in comparison with AHA acids, significantly increasing the protective function of the horny layer of the epidermis, therefore increasing the skin’s resistance to chemical reactions.

These peelings are mild and can be used even by people with acids allergy or hypersensitivity to any components, because indications for use of PHA peels are generally the same of AHA. (Retinoic acid or glycolic peel).

Polyhydroxy acids have been proven to reduce the effects of photo aging: wrinkles, hyper pigmentation, dryness and peeling. They are involved in the formation of collagen and elastin fibers.

It is a very delicate skin treatment that can be used as often as you wish to achieve desired result.

In addition, the risk of post-peel symptoms such as redness and swelling is significantly reduced avoiding post-inflammatory pigmentation.

PHA don’t require a basic neutralizer application after the treatment and can be washed off with water only.

Capable of being used at any time of the year. 


PHA PEEL acne sebhorrea photo aging skin hyperpigmentation skin aging scars ingrown hair mesoinstitute barcelona



Gluconolactone is an active ingredient that treats skin very gently without affecting deeper layers.

The effect is very similar to that of AHA’s (fruit acids like glycolic or lactic acid), but as a type of polyhydroxy acid gluconolactone is more beneficial.

As it contains five hydroxyl groups, it has more hydrating properties compared to alpha hydroxy acid with only one hydroxyl group.

Since it is a larger molecule (having a three-dimensional molecule 178 Da), gluconolactone penetrates the skin slowly without burning it like the other chemical peels with alternative active ingredients do. That’s why non-irritating gluconolactone is perfect even for dry and hypersensitive skin peel.

photoagening, wrinkles, hyperpigmentation, dryness

Anti-inflammatory and antioxidant effects, boost of skin`s immune system.

Gluconolactone is a natural antioxidant which is as effective as vitamin C and vitamin E.

Gluconolactone blocks the synthesis of pro-interleukin-1, which can cause increased inflammation.

Gluconolactone has the ability to transfer water molecules playing a central role in skin moisturizing.

As a chelating agent, gluconolactone has the ability to bind and remove free radicals from the body. The oxidation process, caused by overabundance of iron and UV-rays influence, occurs in skin pigmentation that is a typical sign of photo ageing. Gluconolactone helps to bind free iron ions preventing the oxidation process and consequences of UV-radiation.

Gluconolactone initiates processes that precede the production of hyaluronic acid in keratinocytes and fibroblasts, as well as synthesis in matrix metalloproteinase and collagen. No gender skin care. 


  • Improves skin hydration.
  • Provides smoothing fine lines and wrinkles.
  • Increases skin elasticity.


Dead skin cells are removed gently, causing no skin irritation.

Gluconolactone is used for inflammatory skin diseases accompanied by hyperkeratosis: psoriasis, acne, dermatitis, anti-aging as a means of prevention and correction of age changes of skin, especially sensitive.

Due to the absence of irritating action do not require neutralization may be conducted often enough to achieve a noticeable effect.

Gluconolactone does not cause irritation or sensitization of the skin and mucous membranes.


Bottle      50 mL      Reference      160558


(called summer acid)

Derived from plant extracts, Lactobionic acid (4-O-β-galactopyranosyl-D-gluconic acid) belongs to polyhydroxy acids. Formed by oxidation of milk sugar (a disaccharide named lactose), it consists of gluconic acid and galactose bonded via an ether linkage.

Polyhydroxy acids penetrate the skin gradually, layer by layer. Due to this fact, their use in peel treatments does not cause strong burning sensation and irritation of skin.

Lactobionic acid is a mild exfoliant that smoothes and resurfaces without causing irritation or redness. Thanks to minimal irritative effect, it can be successfully performed even on sensitive skin that is prone to acne.

It has high biocompatibility with human skin. Skin easily adjusts to the lactobionic acid; when all stages of the chemical peel are performed properly, no severe flaking, itching, or hyperemia occur.

Lactobionic acid can function as a link between iron ions, providing strong antioxidant effect. It removes free radical intermediates and protects skin from dangerous UV radiation.

Lactobionic acid inhibits matrix metalloproteinase, which are the main cause of skin aging. They destroy the major components of the extracellular matrix of the skin, collagen in particular, causing elasticity loss, deep wrinkles and a sagging face.

photoagening, wrinkles, hyperpigmentation, dryness

Lactobionic acid helps to moisturize skin. Lactobionic acid creates a water film on the surface of skin, which helps to tackle signs of skin dryness, itching, and tightness for a long time.

It is capable of being used at any time of the year. Lactobionic acid effectively protects skin from UV radiation. No gender skin care.


  • Hyper-pigmentation.
  • Stimulates exfoliation process.
  • Lightens skin.
  • Increase skin hydration.


Dead skin cells are removed gently, causing no skin irritation.

Skin becomes smoother, affecting fibroblasts, and increasing collagen production, this kind of peel helps to rejuvenate and lift skin and removes even deep wrinkles.

Acne is reduced, thanks to deep cleansing combined with smoothing and anti-inflammatory properties, reducing the amount of pimples and blackheads.


Bottle       50 mL      Reference      160565


For external use only. Do not apply to broken or peeling skin. Immediately rinse with water and discontinue use if excessive redness or irritation occurs. Do not store once open. Keep out of reach of children. Open carefully. Avoid contact with the eyes.

General information:

All products are dully registered as a topical cosmetics. and/or  a chemical exfoliant. The manufacturer or distributor are not responsible in any case of any kind of damages caused by third parties or adverse effects. 

For more information or enquires please contact us:

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